STAT5 Transcription Factor
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
Year introduced: 2006(1992)
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Subheadings:
Tree Number(s): D12.644.360.024.342.500, D12.776.157.057.186.500, D12.776.476.024.430.500, D12.776.930.840.500
MeSH Unique ID: D050799
Entry Terms:
- Factor, STAT5 Transcription
- Transcription Factor, STAT5
- Signal Transducer and Activator of Transcription 5
- STAT5 Protein
- STAT5b Transcription Factor
- Transcription Factor, STAT5b
- STAT5b Protein
- Signal Transducer and Activator of Transcription 5B
- STAT5beta Protein
- STAT5a Transcription Factor
- Transcription Factor, STAT5a
- STAT5a Protein
- Mammary Gland Factor
- Mammary Gland-Specific Nuclear Factor
- Mammary Gland Specific Nuclear Factor
- Signal Transducer and Activator of Transcription 5A
- STAT5alpha Protein