Core Binding Factor alpha Subunits

A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.

Year introduced: 2006(1987)

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Tree Number(s): D12.776.930.155.200

MeSH Unique ID: D050657

Entry Terms:

• Polyomavirus Enhancer A Binding Protein 2
• Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
• Runt Domain Factor
• Runx Proteins
• Acute Myeloid Leukemia Proteins
• PEBP2A Transcription Factors
• Transcription Factors, PEBP2A
• Core Binding Factor alpha Proteins

Previous Indexing:

• DNA-Binding Proteins (1987-2005)
• Neoplasm Proteins (1997-2005)
• Transcription Factors (1987-2005)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Core Binding Factors
Core Binding Factor alpha Subunits
Core Binding Factor Alpha 1 Subunit
Core Binding Factor Alpha 2 Subunit
Core Binding Factor Alpha 3 Subunit