Nesidioblastosis
An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.
Year introduced: 2005
PubMed search builder options
Subheadings:
Tree Number(s): C06.689.150.500, C16.614.200.500, C18.452.394.968.250.500, C18.452.394.984.200.500
MeSH Unique ID: D046768
Entry Terms:
- Nesidioblastoses
- Hyperinsulinism, Familial, with Pancreatic Nesidioblastosis
- Nesidioblastosis of Pancreas
- Pancreas Nesidioblastoses
- Pancreas Nesidioblastosis
- Pancreatic Nesidioblastosis
- Nesidioblastoses, Pancreatic
- Nesidioblastosis, Pancreatic
- Pancreatic Nesidioblastoses
Previous Indexing:
See Also: