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Fusion Regulatory Protein-1

A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.

Year introduced: 2018 (1988)

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Tree Number(s): D12.776.157.530.200.374.750.500, D12.776.157.530.200.500.500.500, D12.776.157.530.937.313.500, D12.776.543.585.200.374.750.500, D12.776.543.585.200.500.500.500, D12.776.543.585.937.313.500

MeSH Unique ID: D027261

Entry Terms:

  • Fusion Regulatory Protein 1
  • Regulatory Protein-1, Fusion
  • 4F2-antigen
  • CD98 Antigens
  • FRP-1 protein
  • FRP 1 protein
  • Antigen 4F2
  • Antigens, CD98
  • CD98 Antigen
  • Antigen, CD98
  • 4F2 Antigen
  • CD98 Transport Proteins
  • Transport Proteins, CD98
  • Human 4F2 Antigen
  • 4F2 Antigen, Human
  • Human 4F2 Cell-Surface Antigen
  • Human 4F2 Cell Surface Antigen
  • Human Lymphocyte Activation Antigen 4F2
  • H4F2 Antigen

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