Carboxypeptidase B2
A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.
Year introduced: 2015 (2002)
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Subheadings:
Tree Number(s): D08.811.277.656.350.245.125, D08.811.277.656.350.555.225, D08.811.277.656.675.555.225, D08.811.277.656.837.092
MeSH Unique ID: D025901
Registry Number: EC 3.4.17.20
Entry Terms:
- Arginine Carboxypeptidase
- Carboxypeptidase R
- Carboxypeptidase B2, Plasma
- Plasma Carboxypeptidase B2
- Thrombin-Activatable Fibrinolysis Inhibitor
- Thrombin Activatable Fibrinolysis Inhibitor
- Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
- Carboxypeptidase U
- Procarboxypeptidase U
- Plasma Procarboxypeptidase B
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