Isochromosomes

Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion.

Year introduced: 1995

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Tree Number(s): A11.284.187.570, C23.550.210.430, G05.360.162.570, G05.365.590.175.430

MeSH Unique ID: D018404

Entry Terms:

• Isochromosome

Previous Indexing:

• Chromosome Aberrations (1966-1994)
• specific chromosome (1966-1994)

All MeSH Categories
Anatomy Category
Cells
Cellular Structures
Chromosomes
Isochromosomes

All MeSH Categories
Diseases Category
Pathological Conditions, Signs and Symptoms
Pathologic Processes
Chromosome Aberrations
Isochromosomes

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Phenomena and Processes Category
Genetic Phenomena
Genetic Structures
Chromosomes
Isochromosomes

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Genetic Variation
Mutation
Chromosome Aberrations
Isochromosomes