ISCOMs

A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines.

Year introduced: 1992

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Tree Number(s): D20.215.894.860.449

MeSH Unique ID: D016882

Entry Terms:

• Immuno-Stimulating Complexes
• Complexes, Immuno-Stimulating
• Immuno Stimulating Complexes
• Immunostimulating Complexes
• Complexes, Immunostimulating
• ISCOM

Previous Indexing:

• Adjuvants, Immunologic (1985-1991)
• Viral Vaccines (1985-1991)

See Also:

• Saponins

Pharmacologic Action:

• Adjuvants, Immunologic

All MeSH Categories
Chemicals and Drugs Category
Complex Mixtures
Biological Products
Vaccines
Vaccines, Subunit
ISCOMs