Radioimmunotherapy
Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).
Year introduced: 1992
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Subheadings:
Tree Number(s): E02.095.465.425.750, E02.186.750, E02.815.520
MeSH Unique ID: D016499
Entry Terms:
- Radioimmunotherapies
- Immunoradiotherapy
- Immunoradiotherapies
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