DNA Restriction-Modification Enzymes

Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.

Year introduced: 1989

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D08.811.150

MeSH Unique ID: D015280

Entry Terms:

• Enzymes, DNA Restriction-Modification
• Restriction-Modification Enzymes, DNA
• Restriction Modification System
• Modification System, Restriction
• System, Restriction Modification
• DNA Restriction-Modification Enzyme
• Enzyme, DNA Restriction-Modification
• Restriction-Modification Enzyme, DNA
• DNA Restriction Modification Enzyme
• DNA Restriction Modification Enzymes
• Restriction-Modification System
• System, Restriction-Modification
• Restriction Modification Systems
• Modification Systems, Restriction
• Systems, Restriction Modification
• Restriction-Modification Systems
• Systems, Restriction-Modification

Previous Indexing:

• DNA Restriction Enzymes (1975-1988)
• Methyltransferases (1971-1988)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
DNA Restriction-Modification Enzymes
DNA Modification Methylases
DNA Restriction Enzymes
Deoxyribonucleases, Type I Site-Specific
Deoxyribonucleases, Type II Site-Specific +
Deoxyribonucleases, Type III Site-Specific