Quinidine
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
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Subheadings:
Tree Number(s): D03.132.206.636, D03.605.687.637, D03.633.100.810.699
MeSH Unique ID: D011802
Registry Number: ITX08688JL
Entry Terms:
- Chinidin
- Quinidine Sulfate
- Sulfate, Quinidine
- Quinora
- Adaquin
- Apo-Quinidine
- Apo Quinidine
- Quincardine
- Quinidex
Pharmacologic Action: