Protein Kinase C

An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.

Year introduced: 1986

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Tree Number(s): D08.811.913.696.620.682.700.725, D12.776.476.563.725

MeSH Unique ID: D011493

Registry Number: EC 2.7.11.13

Entry Terms:

• Calcium-Activated Phospholipid-Dependent Kinase
• Calcium Activated Phospholipid Dependent Kinase
• Phospholipid-Dependent Kinase, Calcium-Activated
• Calcium Phospholipid-Dependent Protein Kinase
• Calcium Phospholipid Dependent Protein Kinase
• Phospholipid-Sensitive Calcium-Dependent Protein Kinase
• Phospholipid Sensitive Calcium Dependent Protein Kinase
• PKC Serine-Threonine Kinase
• PKC Serine Threonine Kinase
• Serine-Threonine Kinase, PKC
• Protein Kinase M

Previous Indexing:

• Protein Kinases (1973-1985)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein Serine-Threonine Kinases
Protein Kinase C
Protein Kinase C-alpha
Protein Kinase C beta
Protein Kinase C-delta
Protein Kinase C-epsilon
Protein Kinase C-theta

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Protein Kinase C
Protein Kinase C-alpha
Protein Kinase C beta
Protein Kinase C-delta
Protein Kinase C-epsilon
Protein Kinase C-theta