Phleomycins

Water-soluble, copper-containing low molecular weight polypeptides obtained from the culture medium of Streptomyces verticillus. They are specific inhibitors of DNA synthesis in bacteria and have been found to act as antitumor agents. They have also been used against rust fungi of plants.

Year introduced: 1991(1981)

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Tree Number(s): D09.400.420.110.710, D12.644.233.110.710

MeSH Unique ID: D010692

Entry Terms:

• Phleomycin

Previous Indexing:

• Antibiotics (1971-1974)
• Antibiotics, Antineoplastic (1971-1974)
• Peptides (1971-1974)

Pharmacologic Action:

• Antibiotics, Antineoplastic
• Nucleic Acid Synthesis Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Carbohydrates
Glycoconjugates
Glycopeptides
Bleomycin
Phleomycins

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Glycopeptides
Bleomycin
Phleomycins