Pharmacokinetics

Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.

Year introduced: 1988

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G03.787, G07.690.725

MeSH Unique ID: D010599

Entry Terms:

• Drug Kinetics
• Kinetics, Drug
• LADMER
• Liberation, Absorption, Distribution, Metabolism, Elimination, and Response
• ADMET
• ADME-Tox
• Absorption, Distribution, Metabolism, Elimination, and Toxicology
• ADME
• Absorption, Distribution, Metabolism, and Elimination

Previous Indexing:

• Kinetics (1966-1987)
• specific Category D heading/metabolism (1966-1987)

All MeSH Categories
Phenomena and Processes Category
Metabolism
Pharmacokinetics
Absorption
Absorption, Physiological +
Area Under Curve
Biological Availability
Biotransformation
Activation, Metabolic
Inactivation, Metabolic +
Drug Elimination Routes
Cutaneous Elimination
Hepatobiliary Elimination
Intestinal Elimination
Lacrimal Elimination
Lacteal Elimination
Pulmonary Elimination
Renal Elimination
Salivary Elimination
Drug Liberation
Therapeutic Equivalency
Tissue Distribution

All MeSH Categories
Phenomena and Processes Category
Physiological Phenomena
Pharmacological and Toxicological Phenomena
Pharmacokinetics
Absorption
Absorption, Physiological +
Area Under Curve
Biological Availability
Biotransformation
Activation, Metabolic
Inactivation, Metabolic +
Chronopharmacokinetics
Drug Elimination Routes
Cutaneous Elimination
Hepatobiliary Elimination
Intestinal Elimination
Lacrimal Elimination
Lacteal Elimination
Pulmonary Elimination
Renal Elimination
Salivary Elimination
Drug Liberation
Metabolic Clearance Rate
Therapeutic Equivalency
Tissue Distribution