Ochronosis

The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).

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Tree Number(s): C23.550.744

MeSH Unique ID: D009794

Entry Terms:

• Ochronoses

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Diseases Category
Pathological Conditions, Signs and Symptoms
Pathologic Processes
Ochronosis