Melanocyte-Stimulating Hormones
Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS OF HYPOTHALAMUS.
Year introduced: 2006(1963)
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Subheadings:
Tree Number(s): D06.472.699.327.935.531.750, D06.472.699.631.525.600.531.750, D12.644.400.400.935.531.750, D12.644.400.460, D12.644.548.365.935.531.750, D12.644.548.691.525.690.531.750, D12.776.631.650.405.935.531.750, D12.776.631.650.460
MeSH Unique ID: D009074
Registry Number: 9002-79-3
Entry Terms:
- Melanocyte Stimulating Hormones
- Melanocyte-Stimulating Hormone
- Hormone, Melanocyte-Stimulating
- Melanotropin
- MSH
- Melanophore-Stimulating Hormone
- MSH (Melanocyte-Stimulating Hormones)
- Melanocyte Stimulating Hormone
- Hormone, Melanocyte Stimulating
- Stimulating Hormone, Melanocyte
- Melanophore Stimulating Hormone
- Hormone, Melanophore Stimulating
- Stimulating Hormone, Melanophore
Pharmacologic Action: