Mechlorethamine
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
Year introduced: MECHLORETHAMINE OXIDE was heading 1963-1979
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Subheadings:
Tree Number(s): D02.455.526.728.650.529
MeSH Unique ID: D008466
Registry Number: 50D9XSG0VR
Entry Terms:
- Chlorethazine
- Chlormethine
- Mustine
- Methylchlorethamine
- Nitrogen Mustard
- Bis(2-chloroethyl)methylamine
- Mechlorethamine Oxide
- Nitrogranulogen
- Nitromin
- Embichin
- Mechlorethamine Hydrochloride
- Hydrochloride, Mechlorethamine
- Mustargen
- NSC-762
- NSC762
- NSC 762
- Mechlorethamine N-Oxide
- Mechlorethamine N Oxide
- Nitrogen Mustard N-Oxide
- Nitrogen Mustard N Oxide
- N-Oxide, Nitrogen Mustard
- Mechlorethamine Hydrochloride N-Oxide
- Hydrochloride N-Oxide, Mechlorethamine
- Mechlorethamine Hydrochloride N Oxide
- N-Oxide, Mechlorethamine Hydrochloride
- Cloramin
- NSC-10107
- NSC10107
- NSC 10107
- Caryolysine
- Mitomen
Pharmacologic Action: