Leucyl Aminopeptidase
A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.
Year introduced: 1999(1965)
PubMed search builder options
Subheadings:
Tree Number(s): D08.811.277.656.350.100.511, D08.811.277.656.350.555.700, D08.811.277.656.675.555.700
MeSH Unique ID: D007931
Registry Number: EC 3.4.11.1
Entry Terms:
- Aminopeptidase, Leucyl
- Cytosol Aminopeptidase
- Aminopeptidase, Cytosol
- L-Leucylnaphthylamidase
- Leucine Aminopeptidase
- Aminopeptidase, Leucine
- Zinc-Manganese-Leucine Aminopeptidase
- Aminopeptidase, Zinc-Manganese-Leucine
- Zinc Manganese Leucine Aminopeptidase
- Peptidase S
- Methoxyleucine Aminopeptidase
- Aminopeptidase, Methoxyleucine