Interleukin-1
A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Year introduced: 1990(1983)
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Tree Number(s): D12.644.276.374.465.010, D12.644.276.374.500.400, D12.776.467.374.465.010, D12.776.467.374.500.400, D23.529.374.465.131, D23.529.374.500.400
MeSH Unique ID: D007375
Entry Terms:
- Interleukin 1
- Epidermal Cell Derived Thymocyte-Activating Factor
- Epidermal Cell Derived Thymocyte Activating Factor
- IL-1
- Interleukin I
- Lymphocyte-Activating Factor
- Lymphocyte Activating Factor
- Macrophage Cell Factor
- T Helper Factor
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