Immunosuppressive Agents

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Year introduced: 1966(1964)

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Tree Number(s): D27.505.696.477.656

MeSH Unique ID: D007166

Entry Terms:

• Agents, Immunosuppressive
• Immunosuppressive Agent
• Agent, Immunosuppressive
• Immunosuppressant
• Immunosuppressants

See Also:

• Antilymphocyte Serum
• Antirheumatic Agents

All MeSH Categories
Chemicals and Drugs Category
Chemical Actions and Uses
Pharmacologic Actions
Physiological Effects of Drugs
Immunologic Factors
Immunosuppressive Agents
Complement Inactivating Agents
Bradykinin B2 Receptor Antagonists
Interleukin-6 Inhibitors
Interleukin Inhibitors
MTOR Inhibitors
Myeloablative Agonists
Sphingosine 1 Phosphate Receptor Modulators