GTP Cyclohydrolase
(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).
Year introduced: 1991(1975)
PubMed search builder options
Subheadings:
Tree Number(s): D08.811.277.151.300
MeSH Unique ID: D006136
Registry Number: EC 3.5.4.16
Entry Terms:
- Cyclohydrolase, GTP
- 7,8-Dihydroneopterintriphosphate Synthetase
- 7,8 Dihydroneopterintriphosphate Synthetase
- Synthetase, 7,8-Dihydroneopterintriphosphate
- GTP 8-Formylhydrolase
- 8-Formylhydrolase, GTP
- GTP 8 Formylhydrolase
- GTP Dihydrolase
- Dihydrolase, GTP
- GTP Ring-Opening Enzyme
- GTP Ring Opening Enzyme
- Ring-Opening Enzyme, GTP
- GTP Cyclohydrolase I
- Cyclohydrolase I, GTP
- GTP Cyclohydrolase II
- Cyclohydrolase II, GTP
Previous Indexing: