Epilepsy, Tonic-Clonic
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
Year introduced: 1992(1963)
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Subheadings:
Tree Number(s): C10.228.140.490.375.290
MeSH Unique ID: D004830
Entry Terms:
- Epilepsies, Tonic-Clonic
- Epilepsy, Tonic Clonic
- Tonic-Clonic Epilepsies
- Tonic-Clonic Epilepsy
- Convulsions, Grand Mal
- Convulsion, Grand Mal
- Grand Mal Convulsion
- Grand Mal Convulsions
- Epilepsy, Grand Mal
- Grand Mal Epilepsy
- Epilepsy, Major
- Major Epilepsies
- Major Epilepsy
- Grand Mal Seizure Disorder
- Major Motor Seizure Disorder
- Seizure Disorder, Grand Mal
- Seizure Disorder, Major Motor
- Seizure Disorder, Tonic Clonic
- Tonic Clonic Convulsions
- Convulsions, Tonic Clonic
- Convulsion, Tonic Clonic
- Tonic Clonic Convulsion
- Tonic-Clonic Convulsion Disorder
- Convulsion Disorders, Tonic-Clonic
- Convulsion Disorder, Tonic-Clonic
- Disorders, Tonic-Clonic Convulsion
- Disorder, Tonic-Clonic Convulsion
- Tonic Clonic Convulsion Disorder
- Tonic-Clonic Convulsion Disorders
- Tonic-Clonic Convulsion Syndrome
- Convulsion Syndromes, Tonic-Clonic
- Convulsion Syndrome, Tonic-Clonic
- Syndromes, Tonic-Clonic Convulsion
- Syndrome, Tonic-Clonic Convulsion
- Tonic Clonic Convulsion Syndrome
- Tonic-Clonic Convulsion Syndromes
- Tonic-Clonic Seizure Disorder
- Disorders, Tonic-Clonic Seizure
- Disorder, Tonic-Clonic Seizure
- Seizure Disorders, Tonic-Clonic
- Seizure Disorder, Tonic-Clonic
- Tonic Clonic Seizure Disorder
- Tonic-Clonic Seizure Disorders
- Tonic-Clonic Seizure Syndrome
- Seizure Syndromes, Tonic-Clonic
- Seizure Syndrome, Tonic-Clonic
- Syndromes, Tonic-Clonic Seizure
- Syndrome, Tonic-Clonic Seizure
- Tonic Clonic Seizure Syndrome
- Tonic-Clonic Seizure Syndromes
- Cryptogenic Tonic-Clonic Epilepsy
- Cryptogenic Tonic-Clonic Epilepsies
- Cryptogenic Tonic Clonic Epilepsy
- Epilepsies, Cryptogenic Tonic-Clonic
- Epilepsy, Cryptogenic Tonic-Clonic
- Tonic-Clonic Epilepsies, Cryptogenic
- Tonic-Clonic Epilepsy, Cryptogenic
- Epilepsy, Tonic-Clonic, Cryptogenic
- Epilepsy, Tonic-Clonic, Familial
- Familial Tonic-Clonic Epilepsy
- Epilepsies, Familial Tonic-Clonic
- Epilepsy, Familial Tonic-Clonic
- Familial Tonic-Clonic Epilepsies
- Familial Tonic Clonic Epilepsy
- Tonic-Clonic Epilepsies, Familial
- Tonic-Clonic Epilepsy, Familial
- Epilepsy, Tonic-Clonic, Symptomatic
- Symptomatic Tonic-Clonic Epilepsy
- Epilepsies, Symptomatic Tonic-Clonic
- Epilepsy, Symptomatic Tonic-Clonic
- Symptomatic Tonic-Clonic Epilepsies
- Symptomatic Tonic Clonic Epilepsy
- Tonic-Clonic Epilepsies, Symptomatic
- Tonic-Clonic Epilepsy, Symptomatic