DNA Polymerase II
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents.
Year introduced: 1984(1977)
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Subheadings:
Tree Number(s): D08.811.913.696.445.308.300.230
MeSH Unique ID: D004257
Registry Number: EC 2.7.7.7
Entry Terms:
- DNA Pol II
- DNA Polymerase epsilon
- DNA-Dependent DNA Polymerase II
- DNA Dependent DNA Polymerase II
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