Crossing Over, Genetic

The reciprocal exchange of segments at corresponding positions along pairs of homologous CHROMOSOMES by symmetrical breakage and crosswise rejoining forming cross-over sites (HOLLIDAY JUNCTIONS) that are resolved during CHROMOSOME SEGREGATION. Crossing-over typically occurs during MEIOSIS but it may also occur in the absence of meiosis, for example, with bacterial chromosomes, organelle chromosomes, or somatic cell nuclear chromosomes.

Year introduced: 2005(1968)

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Tree Number(s): G05.728.615.200

MeSH Unique ID: D003434

Entry Terms:

• Genetic Crossing Over
• Crossing Over
• Crossing Overs
• Crossing-Over, Genetic
• Genetic Crossing-Over

Previous Indexing:

• Cytogenetics (1967)
• Genetics (1966-1967)

See Also:

• Sister Chromatid Exchange
• Chromosome Pairing
• Pachytene Stage

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Recombination, Genetic
Homologous Recombination
Crossing Over, Genetic