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Coagulase

Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.

Year introduced: 1966(1964)

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Subheadings:

Tree Number(s): D08.811.277.656.300.174, D12.776.097.181

MeSH Unique ID: D003030

Entry Terms:

  • Staphylococcal Clumping Factor
  • Clumping Factor, Staphylococcal
  • Factor, Staphylococcal Clumping
  • Clumping Factor (Staphylococcal)
  • Staphylocoagulase
  • Staphylococcus aureus clone pSCa2 of Coagulase
  • Staphylococcus aureus strain 213 of Coagulase
  • Staphylococcus aureus strain 8325-4 of Coagulase
  • Staphylococcus aureus strain 8325 4 of Coagulase

Pharmacologic Action:

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