Bromouracil

5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.

Year introduced: 1974(1971)

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Tree Number(s): D03.383.742.698.875.237

MeSH Unique ID: D001976

Registry Number: 4HK400G5UO

Entry Terms:

• 5-Bromouracil
• 5 Bromouracil
• Bromuracil

Previous Indexing:

• Uracil (1966-1970)

Pharmacologic Action:

• Antimetabolites
• Mutagens

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyrimidines
Pyrimidinones
Uracil
Bromouracil