Solute Carrier Family 12

Inorganic cation-chloride cotransporters mediating the movement of inorganic SODIUM and/or POTASSIUM cations, coupled to the movement of CHLORIDE anions. The solute carrier 12 (SLC12) family can be divided into Na+-dependent SLC12A1-A3 (NKCC1, NKCC2, and NCC) and Na+-independent SLC12A4-A7 (KCC1-KCC4).

Year introduced: 2024

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Tree Number(s): D12.776.157.530.450.250.910, D12.776.157.530.450.625.875, D12.776.543.585.450.250.918, D12.776.543.585.450.625.875

MeSH Unique ID: D000096925

Entry Terms:

• SLC12A Transporters

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
Membrane Transport Proteins
Ion Pumps
Cation Transport Proteins
Solute Carrier Family 12

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Carrier Proteins
Membrane Transport Proteins
Ion Pumps
Symporters
Solute Carrier Family 12
K Cl- Cotransporters
Solute Carrier Family 12, Member 4
Sodium-Potassium-Chloride Symporters
Solute Carrier Family 12, Member 1
Solute Carrier Family 12, Member 2

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Membrane Transport Proteins
Ion Pumps
Cation Transport Proteins
Solute Carrier Family 12

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Membrane Transport Proteins
Ion Pumps
Symporters
Solute Carrier Family 12