Neuroligins

Postsynaptic cell-adhesion molecules that bind presynaptic NEUREXINS to form calcium-dependent trans-synaptic adhesions. Neuroligins recruit synaptic scaffolding proteins (e.g., PSD-95) via their PDZ DOMAIN. The distribution and interaction with neurexins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neuroligins or neurexins are associated with cognitive diseases such as AUTISM SPECTRUM DISORDER.

Year introduced: 2024

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D09.400.430.890.200.250.520.894, D12.776.395.550.200.250.520.894, D12.776.543.550.200.250.520.894, D12.776.631.641, D23.050.301.350.250.520.894

MeSH Unique ID: D000096785

Entry Terms:

• Neuroligin

Previous Indexing:

• Nerve Tissue Proteins (1992-2023)

All MeSH Categories
Chemicals and Drugs Category
Carbohydrates
Glycoconjugates
Glycoproteins
Membrane Glycoproteins
Cell Adhesion Molecules
Cell Adhesion Molecules, Neuronal
Neural Cell Adhesion Molecules
Neuroligins

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Glycoproteins
Membrane Glycoproteins
Cell Adhesion Molecules
Cell Adhesion Molecules, Neuronal
Neural Cell Adhesion Molecules
Neuroligins

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Membrane Glycoproteins
Cell Adhesion Molecules
Cell Adhesion Molecules, Neuronal
Neural Cell Adhesion Molecules
Neuroligins

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Nerve Tissue Proteins
Neuroligins

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Antigens
Antigens, Surface
Cell Adhesion Molecules
Cell Adhesion Molecules, Neuronal
Neural Cell Adhesion Molecules
Neuroligins