Angiotensin-Converting Enzyme 2
A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
Year introduced: 2021 (2000)
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Subheadings:
Tree Number(s): D08.811.277.656.350.245.042
MeSH Unique ID: D000085962
Registry Number: EC 3.4.17.23
Entry Terms:
- Angiotensin-Converting Enzyme-Related Carboxypeptidase
- Angiotensin Converting Enzyme Related Carboxypeptidase
- Carboxypeptidase, Angiotensin-Converting Enzyme-Related
- Angiotensin Converting Enzyme 2
- ACE2 Enzyme
- ACE2 Angiotensin-Converting Enzyme Protein 2
- ACE2 Angiotensin Converting Enzyme Protein 2
- ACE-Related Carboxypeptidase
- ACE Related Carboxypeptidase
- Carboxypeptidase, ACE-Related
- ACE2 Protein