Lapatinib

A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2.

Year introduced: 2019 (2004)

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Tree Number(s): D03.633.100.786.516

MeSH Unique ID: D000077341

Registry Number: 0VUA21238F

Entry Terms:

• N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine
• GW572016
• GW 572016
• GW-572016
• Lapatinib Ditosylate
• Tykerb
• GW 282974X
• GW-282974X
• GW282974X

Pharmacologic Action:

• Antineoplastic Agents
• Tyrosine Kinase Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Quinazolines
Lapatinib