Agammaglobulinaemia Tyrosine Kinase

A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.

Year introduced: 2019 (1993)

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Tree Number(s): D08.811.913.696.620.682.725.025, D12.776.476.568.025

MeSH Unique ID: D000077329

Registry Number: EC 2.7.10.2

Entry Terms:

• Kinase, Agammaglobulinaemia Tyrosine
• Tyrosine Kinase, Agammaglobulinaemia
• B Cell Progenitor Kinase
• Bruton's Tyrosine Kinase
• Brutons Tyrosine Kinase
• Bruton Tyrosine Kinase
• Kinase, Bruton's Tyrosine
• Tyrosine Kinase, Bruton's

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
Phosphotransferases
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein-Tyrosine Kinases
Agammaglobulinaemia Tyrosine Kinase

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Agammaglobulinaemia Tyrosine Kinase