Survivin
An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.
Year introduced: 2019
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Subheadings:
Tree Number(s): D12.644.360.075.437.625, D12.776.167.576, D12.776.220.600.450.495, D12.776.476.075.437.625
MeSH Unique ID: D000077022
Entry Terms:
- Baculoviral IAP Repeat-containing Protein 5
- Baculoviral IAP Repeat containing Protein 5
- BIRC5 Protein
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