Immunoglobulin Light-chain Amyloidosis
A nonproliferative disorder of PLASMA CELLS characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
Year introduced: 2018(2010)
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Subheadings:
Tree Number(s): C04.557.595.250, C18.452.845.500.550, C20.683.515.507, C20.683.780.565
MeSH Unique ID: D000075363
Entry Terms:
- Immunoglobulin Light-chain Amyloidoses
- Immunoglobulin Light chain Amyloidosis
- AL Amyloidosis
- AL Amyloidoses
- Primary Amyloidosis
- Amyloidoses, Primary
- Primary Amyloidoses
- Monoclonal Immunoglobulin Deposition Disease
- Primary Systemic Amyloidosis
- Amyloidoses, Primary Systemic
- Amyloidosis, Primary Systemic
- Primary Systemic Amyloidoses
- Systemic Amyloidoses, Primary
- Systemic Amyloidosis, Primary
- Amyloidosis, Primary
- Amyloidosis, Immunoglobulin Light-chain
- Amyloidosis, Immunoglobulin Light chain