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MYND Domains

Zinc finger domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic proteins, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of cysteine and histidine residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology, similar to LIM domains (see LIM DOMAIN PROTEINS) and RING FINGER DOMAINS. MYND domains function as protein interaction motifs and have affinity for PROLINE-RICH PROTEIN DOMAINS.

Year introduced: 2018

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Subheadings:

Tree Number(s): G02.111.570.820.709.275.500.985.375, G02.111.570.820.709.275.750.500.474

MeSH Unique ID: D000074608

Entry Terms:

  • Domain, MYND
  • Domains, MYND
  • Zinc Finger MYND-Type
  • Zinc Finger MYND Type
  • MYND Motif
  • Motif, MYND
  • Motifs, MYND
  • MYND Motifs
  • MYND Domain

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