Aldo-Keto Reductases
A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates.
Year introduced: 2018
PubMed search builder options
Subheadings:
Tree Number(s): D08.811.682.047.150.700.156, D08.811.682.047.820.284
MeSH Unique ID: D000074408
Registry Number: EC 1.1.1.-
Entry Terms:
- Aldo Keto Reductases
- Reductases, Aldo-Keto
- Aldo-Keto Reductase Family
- Aldo Keto Reductase Family
- Aldo-Keto Reductase Superfamily
- Aldo Keto Reductase Superfamily
- Aldo-Keto Reductase
- Aldo Keto Reductase
- Reductase, Aldo-Keto
Previous Indexing: