Solute Carrier Family 22 Member 5
A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency.
Year introduced: 2018
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Subheadings:
Tree Number(s): D12.776.157.530.450.250.812.750, D12.776.157.530.937.612.750, D12.776.543.585.450.250.812.750, D12.776.543.585.937.701.750
MeSH Unique ID: D000074058
Entry Terms:
- Organic Cation-Carnitine Transporter 2
- Organic Cation Carnitine Transporter 2
- SLC22A5 Protein
- OCTN2 Protein
- Sodium-Dependent Carnitine Cotransporter
- Carnitine Cotransporter, Sodium-Dependent
- Sodium Dependent Carnitine Cotransporter
- High-Affinity Carnitine Transporter
- Carnitine Transporter, High-Affinity
- High Affinity Carnitine Transporter
- Transporter, High-Affinity Carnitine
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