Interferon-Induced Helicase, IFIH1
A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.
Year introduced: 2017
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Subheadings:
Tree Number(s): D08.811.913.696.445.735.720.249.875, D12.776.066.125
MeSH Unique ID: D000072640
Registry Number: EC 3.6.4.13
Entry Terms:
- Helicase, IFIH1 Interferon-Induced
- IFIH1 Interferon-Induced Helicase
- Interferon Induced Helicase, IFIH1
- Interferon-Induced Helicase C Domain-Containing Protein 1
- Interferon Induced Helicase C Domain Containing Protein 1
- Melanoma Differentiation-Associated Protein 5
- Melanoma Differentiation Associated Protein 5
- IFIH1 Protein
- CADM-140 Autoantigen
- Autoantigen, CADM-140
- CADM 140 Autoantigen
- Interferon Induced with Helicase C Domain 1
- Helicard
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