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Butyrophilins

A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN).

Year introduced: 2017 (1981)

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Subheadings:

Tree Number(s): D09.400.430.890.114, D12.776.395.550.114, D12.776.543.550.195

MeSH Unique ID: D000071797

Entry Terms:

  • Butyrophilin

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