beta-Arrestins
Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.
Year introduced: 2017 (1992)
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Subheadings:
Tree Number(s): D12.644.360.024.098.525, D12.776.157.057.005.525, D12.776.476.024.104.525, D12.776.543.090.525
MeSH Unique ID: D000071557
Entry Terms:
- beta Arrestins
- beta-Arrestin
- beta Arrestin