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Endoglin

A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.

Year introduced: 2017

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Subheadings:

Tree Number(s): D12.776.543.750.250

MeSH Unique ID: D000071063

Entry Terms:

  • Endoglin Protein
  • CD105 Antigen
  • Antigen, CD105

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