ATP Binding Cassette Transporter, Subfamily G
A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters.
Year introduced: 2019 (2017)
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Subheadings:
Tree Number(s): D09.400.430.890.020.457, D12.776.157.530.100.228, D12.776.395.550.020.457, D12.776.543.550.192.457, D12.776.543.585.100.228
MeSH Unique ID: D000070996
Entry Terms:
- ABCG Proteins
- ABCG Transporters
- ATP Binding Cassette Transporter, Sub-Family G
- ATP Binding Cassette Transporter, Sub Family G
- ABCG Transporter
- Transporter, ABCG
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