pimodivir [Supplementary Concept]

non‐nucleotide inhibitor of the polymerase basic protein 2 (PB2) subunit of the influenza A that is active against H1N1, H7N9 and H5N1, as well as influenza A strains with reduced susceptibility to NAIs

Date introduced: February 18, 2016

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MeSH Unique ID: C000605010

Registry Number: DFC121MXC3

Heading Mapped to:

• Pyridines
• Pyrimidines
• Pyrroles

Entry Terms:

• VX-787
• JNJ-63623872
• (2S,3S)-3-((5-Fluoro-2-(5-fluoro-1H-pyrrolo(2,3-b)pyridin-3-yl)-4-pyrimidinyl)amino)bicyclo(2.2.2)octane-2-carboxylic acid
• Bicyclo(2.2.2)octane-2-carboxylic acid, 3-((5-fluoro-2-(5-fluoro-1H-pyrrolo(2,3-b)pyridin-3-yl)-4-pyrimidinyl)amino)-, (2S,3S)-

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pimodivir