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Sofosbuvir

A uridine monophosphate analog inhibitor of HEPATITIS C VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of CHRONIC HEPATITIS C.

Year introduced: 2016 (2010)

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Tree Number(s): D03.383.742.686.850.877.500, D13.695.740.850.877.500, D13.695.827.919.877.500

MeSH Unique ID: D000069474

Registry Number: WJ6CA3ZU8B

Entry Terms:

  • 2-((5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy)phenoxyphosphorylamino)propionic acid isopropyl ester
  • PSI 7977
  • 7977, PSI
  • PSI-7977
  • PSI7977
  • GS-7977
  • GS7977
  • GS 7977
  • Sovaldi

Pharmacologic Action:

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