Dasatinib

A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB.

Year introduced: 2016 (2004)

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Tree Number(s): D02.886.675.184, D03.383.129.708.198, D03.383.742.148

MeSH Unique ID: D000069439

Registry Number: RBZ1571X5H

Entry Terms:

• N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide
• BMS 354825
• 354825, BMS
• BMS-354825
• BMS354825
• Sprycel
• (18F)-N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide

Pharmacologic Action:

• Antineoplastic Agents
• Tyrosine Kinase Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Sulfur Compounds
Thiazoles
Dasatinib

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Azoles
Thiazoles
Dasatinib

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyrimidines
Dasatinib