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Vitamin B3 deficiency

MedGen UID:
1391948
•Concept ID:
C4317126
•
Disease or Syndrome
Synonyms: Niacin deficiency; Nicotinamide deficiency; Nicotinic acid deficiency; Vitamin PP deficiency
SNOMED CT: Niacin deficiency (418279001); Nicotinamide deficiency (418279001); Nicotinic acid deficiency (418279001); Vitamin B3 deficiency (418279001); Vitamin PP deficiency (418279001)
 
HPO: HP:0100497

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVitamin B3 deficiency

Professional guidelines

PubMed

Protocol for a Case-Control Study to Investigate the Association of Pellagra With Isoniazid Exposure During Tuberculosis Preventive Treatment Scale-Up in Malawi.
Nabity SA, Mponda K, Gutreuter S, Surie D, Williams A, Sharma AJ, Schnaubelt ER, Marshall RE, Kirking HL, Zimba SB, Sunguti JL, Chisuwo L, Chiwaula MJ, Gregory JF, da Silva R, Odo M, Jahn A, Kalua T, Nyirenda R, Girma B, Mpunga J, Buono N, Maida A, Kim EJ, Gunde LJ, Mekonnen TF, Auld AF, Muula AS, Oeltmann JE
Front Public Health 2020;8:551308. Epub 2020 Nov 26 doi: 10.3389/fpubh.2020.551308. PMID: 33324593Free PMC Article

Recent clinical studies

Etiology

Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study.
Nabity SA, Mponda K, Gutreuter S, Surie D, Zimba SB, Chisuwo L, Moffitt A, Williams AM, Sharma AJ, Marshall RE, Chiwaula MJ, da Silva R, Kumwenda T, Chilikutali L, Mwamale S, Nagoli E, Mwenyeheri G, Ngongonda D, Kaunda E, Mtoto F, Mhango V, Mbewe K, Melgar M, Odo M, Jahn A, Buono N, Maida A, Girma B, Kalua T, Nyirenda R, Sunguti J, Woelk G, Gunde LJ, Mekonnen TF, Maphosa T, Kim EJ, Auld AF, Muula AS, Oeltmann JE
Lancet Glob Health 2022 May;10(5):e705-e714. doi: 10.1016/S2214-109X(22)00096-1. PMID: 35427527
Protocol for a Case-Control Study to Investigate the Association of Pellagra With Isoniazid Exposure During Tuberculosis Preventive Treatment Scale-Up in Malawi.
Nabity SA, Mponda K, Gutreuter S, Surie D, Williams A, Sharma AJ, Schnaubelt ER, Marshall RE, Kirking HL, Zimba SB, Sunguti JL, Chisuwo L, Chiwaula MJ, Gregory JF, da Silva R, Odo M, Jahn A, Kalua T, Nyirenda R, Girma B, Mpunga J, Buono N, Maida A, Kim EJ, Gunde LJ, Mekonnen TF, Auld AF, Muula AS, Oeltmann JE
Front Public Health 2020;8:551308. Epub 2020 Nov 26 doi: 10.3389/fpubh.2020.551308. PMID: 33324593Free PMC Article
Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention.
Fania L, Mazzanti C, Campione E, Candi E, Abeni D, Dellambra E
Int J Mol Sci 2019 Nov 26;20(23) doi: 10.3390/ijms20235946. PMID: 31779194Free PMC Article
Correlation of changes in HIF-1α and p53 expressions with vitamin B3 deficiency in skin cancer patients.
Liu T, Yang H, Mou Y, Zhang H
G Ital Dermatol Venereol 2019 Oct;154(5):513-518. Epub 2017 Oct 23 doi: 10.23736/S0392-0488.17.05775-3. PMID: 29064206

Diagnosis

A child with persistent exfoliative dermatitis.
Chin CYL, Chia SY, Koh MJA
Pediatr Dermatol 2023 Nov-Dec;40(6):1121-1123. Epub 2023 Apr 18 doi: 10.1111/pde.15316. PMID: 37970692
Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study.
Nabity SA, Mponda K, Gutreuter S, Surie D, Zimba SB, Chisuwo L, Moffitt A, Williams AM, Sharma AJ, Marshall RE, Chiwaula MJ, da Silva R, Kumwenda T, Chilikutali L, Mwamale S, Nagoli E, Mwenyeheri G, Ngongonda D, Kaunda E, Mtoto F, Mhango V, Mbewe K, Melgar M, Odo M, Jahn A, Buono N, Maida A, Girma B, Kalua T, Nyirenda R, Sunguti J, Woelk G, Gunde LJ, Mekonnen TF, Maphosa T, Kim EJ, Auld AF, Muula AS, Oeltmann JE
Lancet Glob Health 2022 May;10(5):e705-e714. doi: 10.1016/S2214-109X(22)00096-1. PMID: 35427527
Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS.
Sallabi SM, Alhmoudi A, Alshekaili M, Shah I
Molecules 2021 Jul 25;26(15) doi: 10.3390/molecules26154487. PMID: 34361640Free PMC Article
Pellagra in South Africa from 1897 to 2019: a scoping review.
Viljoen M, Bipath P, Tosh C
Public Health Nutr 2021 Jun;24(8):2062-2076. Epub 2021 Mar 26 doi: 10.1017/S1368980021001336. PMID: 33769244Free PMC Article
Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention.
Fania L, Mazzanti C, Campione E, Candi E, Abeni D, Dellambra E
Int J Mol Sci 2019 Nov 26;20(23) doi: 10.3390/ijms20235946. PMID: 31779194Free PMC Article

Therapy

Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study.
Nabity SA, Mponda K, Gutreuter S, Surie D, Zimba SB, Chisuwo L, Moffitt A, Williams AM, Sharma AJ, Marshall RE, Chiwaula MJ, da Silva R, Kumwenda T, Chilikutali L, Mwamale S, Nagoli E, Mwenyeheri G, Ngongonda D, Kaunda E, Mtoto F, Mhango V, Mbewe K, Melgar M, Odo M, Jahn A, Buono N, Maida A, Girma B, Kalua T, Nyirenda R, Sunguti J, Woelk G, Gunde LJ, Mekonnen TF, Maphosa T, Kim EJ, Auld AF, Muula AS, Oeltmann JE
Lancet Glob Health 2022 May;10(5):e705-e714. doi: 10.1016/S2214-109X(22)00096-1. PMID: 35427527
Protocol for a Case-Control Study to Investigate the Association of Pellagra With Isoniazid Exposure During Tuberculosis Preventive Treatment Scale-Up in Malawi.
Nabity SA, Mponda K, Gutreuter S, Surie D, Williams A, Sharma AJ, Schnaubelt ER, Marshall RE, Kirking HL, Zimba SB, Sunguti JL, Chisuwo L, Chiwaula MJ, Gregory JF, da Silva R, Odo M, Jahn A, Kalua T, Nyirenda R, Girma B, Mpunga J, Buono N, Maida A, Kim EJ, Gunde LJ, Mekonnen TF, Auld AF, Muula AS, Oeltmann JE
Front Public Health 2020;8:551308. Epub 2020 Nov 26 doi: 10.3389/fpubh.2020.551308. PMID: 33324593Free PMC Article
Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention.
Fania L, Mazzanti C, Campione E, Candi E, Abeni D, Dellambra E
Int J Mol Sci 2019 Nov 26;20(23) doi: 10.3390/ijms20235946. PMID: 31779194Free PMC Article
Correlation of changes in HIF-1α and p53 expressions with vitamin B3 deficiency in skin cancer patients.
Liu T, Yang H, Mou Y, Zhang H
G Ital Dermatol Venereol 2019 Oct;154(5):513-518. Epub 2017 Oct 23 doi: 10.23736/S0392-0488.17.05775-3. PMID: 29064206

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