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Peau d'orange retinal changes

MedGen UID:
357992
•Concept ID:
C1867453
•
Finding

Professional guidelines

PubMed

Antivascular endothelial growth factor treatment in pseudoxanthoma elasticum patients.
Verbraak FD
Dev Ophthalmol 2010;46:96-106. Epub 2010 Aug 10 doi: 10.1159/000320012. PMID: 20703035

Recent clinical studies

Etiology

Non-exudative macular neovascularization in pseudoxanthoma elasticum.
Marques JP, Bernardes J, Geada S, Soares M, Teixeira D, Farinha C, Pires I, Cachulo ML, Silva R
Graefes Arch Clin Exp Ophthalmol 2021 Apr;259(4):873-882. Epub 2020 Oct 19 doi: 10.1007/s00417-020-04979-z. PMID: 33074374
β-Thalassemia and ocular implications: a systematic review.
Liaska A, Petrou P, Georgakopoulos CD, Diamanti R, Papaconstantinou D, Kanakis MG, Georgalas I
BMC Ophthalmol 2016 Jul 8;16:102. doi: 10.1186/s12886-016-0285-2. PMID: 27390837Free PMC Article
Antivascular endothelial growth factor treatment in pseudoxanthoma elasticum patients.
Verbraak FD
Dev Ophthalmol 2010;46:96-106. Epub 2010 Aug 10 doi: 10.1159/000320012. PMID: 20703035
Hypofluorescent spots in indocyanine green angiography of peau d'orange and fundus.
Shiraki K, Moriwaki M, Matsumoto M, Khono T, Miki T
Int Ophthalmol 1997;21(1):43-50. doi: 10.1023/a:1005898714237. PMID: 9298423
Historical evidence for the genetic heterogeneity of pseudoxanthoma elasticum.
Pope FM
Br J Dermatol 1975 May;92(5):493-509. doi: 10.1111/j.1365-2133.1975.tb03117.x. PMID: 1100089

Diagnosis

Non-exudative macular neovascularization in pseudoxanthoma elasticum.
Marques JP, Bernardes J, Geada S, Soares M, Teixeira D, Farinha C, Pires I, Cachulo ML, Silva R
Graefes Arch Clin Exp Ophthalmol 2021 Apr;259(4):873-882. Epub 2020 Oct 19 doi: 10.1007/s00417-020-04979-z. PMID: 33074374
Peau d'orange and angioid streaks: manifestations of Bruch membrane pathology.
Spaide RF
Retina 2015 Mar;35(3):392-7. doi: 10.1097/IAE.0000000000000420. PMID: 25526100
Fundus autofluorescence in Pseudoxanthoma elasticum.
Finger RP, Charbel Issa P, Ladewig M, Götting C, Holz FG, Scholl HP
Retina 2009 Nov-Dec;29(10):1496-505. doi: 10.1097/IAE.0b013e3181aade47. PMID: 19823106
Hypofluorescent spots in indocyanine green angiography of peau d'orange and fundus.
Shiraki K, Moriwaki M, Matsumoto M, Khono T, Miki T
Int Ophthalmol 1997;21(1):43-50. doi: 10.1023/a:1005898714237. PMID: 9298423
Historical evidence for the genetic heterogeneity of pseudoxanthoma elasticum.
Pope FM
Br J Dermatol 1975 May;92(5):493-509. doi: 10.1111/j.1365-2133.1975.tb03117.x. PMID: 1100089

Therapy

β-Thalassemia and ocular implications: a systematic review.
Liaska A, Petrou P, Georgakopoulos CD, Diamanti R, Papaconstantinou D, Kanakis MG, Georgalas I
BMC Ophthalmol 2016 Jul 8;16:102. doi: 10.1186/s12886-016-0285-2. PMID: 27390837Free PMC Article
The spectrum of ocular alterations in patients with β-thalassemia syndromes suggests a pathology similar to pseudoxanthoma elasticum.
Barteselli G, Dell'arti L, Finger RP, Charbel Issa P, Marcon A, Vezzola D, Mapelli C, Cassinerio E, Cappellini MD, Ratiglia R, Viola F
Ophthalmology 2014 Mar;121(3):709-18. Epub 2013 Dec 4 doi: 10.1016/j.ophtha.2013.10.016. PMID: 24314836
Antivascular endothelial growth factor treatment in pseudoxanthoma elasticum patients.
Verbraak FD
Dev Ophthalmol 2010;46:96-106. Epub 2010 Aug 10 doi: 10.1159/000320012. PMID: 20703035

Prognosis

Antivascular endothelial growth factor treatment in pseudoxanthoma elasticum patients.
Verbraak FD
Dev Ophthalmol 2010;46:96-106. Epub 2010 Aug 10 doi: 10.1159/000320012. PMID: 20703035

Clinical prediction guides

Non-exudative macular neovascularization in pseudoxanthoma elasticum.
Marques JP, Bernardes J, Geada S, Soares M, Teixeira D, Farinha C, Pires I, Cachulo ML, Silva R
Graefes Arch Clin Exp Ophthalmol 2021 Apr;259(4):873-882. Epub 2020 Oct 19 doi: 10.1007/s00417-020-04979-z. PMID: 33074374
β-Thalassemia and ocular implications: a systematic review.
Liaska A, Petrou P, Georgakopoulos CD, Diamanti R, Papaconstantinou D, Kanakis MG, Georgalas I
BMC Ophthalmol 2016 Jul 8;16:102. doi: 10.1186/s12886-016-0285-2. PMID: 27390837Free PMC Article
The spectrum of ocular alterations in patients with β-thalassemia syndromes suggests a pathology similar to pseudoxanthoma elasticum.
Barteselli G, Dell'arti L, Finger RP, Charbel Issa P, Marcon A, Vezzola D, Mapelli C, Cassinerio E, Cappellini MD, Ratiglia R, Viola F
Ophthalmology 2014 Mar;121(3):709-18. Epub 2013 Dec 4 doi: 10.1016/j.ophtha.2013.10.016. PMID: 24314836
Fundus autofluorescence in Pseudoxanthoma elasticum.
Finger RP, Charbel Issa P, Ladewig M, Götting C, Holz FG, Scholl HP
Retina 2009 Nov-Dec;29(10):1496-505. doi: 10.1097/IAE.0b013e3181aade47. PMID: 19823106
Hypofluorescent spots in indocyanine green angiography of peau d'orange and fundus.
Shiraki K, Moriwaki M, Matsumoto M, Khono T, Miki T
Int Ophthalmol 1997;21(1):43-50. doi: 10.1023/a:1005898714237. PMID: 9298423

Recent systematic reviews

β-Thalassemia and ocular implications: a systematic review.
Liaska A, Petrou P, Georgakopoulos CD, Diamanti R, Papaconstantinou D, Kanakis MG, Georgalas I
BMC Ophthalmol 2016 Jul 8;16:102. doi: 10.1186/s12886-016-0285-2. PMID: 27390837Free PMC Article

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