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Abnormal lacrimal duct morphology

MedGen UID:
346938
•Concept ID:
C1858567
•
Anatomical Abnormality; Finding
Synonym: Lacrimal duct abnormalities
 
HPO: HP:0011481

Definition

An abnormality of the lacrimal duct, a duct that drain tears from the conjunctiva, via the lacrimal puncta, into the lacrimal sac. [from HPO]

Professional guidelines

PubMed

Congenital nasolacrimal duct obstruction: clinical guideline.
Sasaki T, Matsumura N, Miyazaki C, Kamao T, Yokoi N, Fujimoto M, Hayami M, Iwasaki A, Mimura M, Murata A, Nakayama T, Shinomiya K, Tanaka H, Ueta Y; Congenital Nasolacrimal Duct Obstruction: Clinical Guideline Preparation Team; Committee for Congenital Nasolacrimal Duct Obstruction Clinical Guideline
Jpn J Ophthalmol 2024 Jul;68(4):367-388. Epub 2024 Aug 16 doi: 10.1007/s10384-024-01064-4. PMID: 39150609
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Treatment of Congenital Nasolacrimal Duct Obstruction.
Nelson LB
J Pediatr Ophthalmol Strabismus 2016 Sep 1;53(5):270. doi: 10.3928/01913913-20160829-01. PMID: 27637019

Recent clinical studies

Etiology

Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO).
Ali MJ
Prog Retin Eye Res 2023 Sep;96:101193. Epub 2023 Jul 1 doi: 10.1016/j.preteyeres.2023.101193. PMID: 37394093
Congenital inner eyelid folds.
Millett M, Hyasat JG, Lueder GT
Ophthalmic Genet 2023 Aug;44(4):401-402. Epub 2023 Jan 13 doi: 10.1080/13816810.2022.2127151. PMID: 36636984
Hereditary disorders affecting the lacrimal system.
Allen RC
Curr Opin Ophthalmol 2014 Sep;25(5):424-31. doi: 10.1097/ICU.0000000000000092. PMID: 25029093
Proboscis lateralis.
Lelli GJ Jr, Maher EA, Milite JP, Dyleski R
Ophthalmic Plast Reconstr Surg 2008 Nov-Dec;24(6):499-501. doi: 10.1097/IOP.0b013e31818b6e57. PMID: 19033859
Midface anomalies in children.
Lowe LH, Booth TN, Joglar JM, Rollins NK
Radiographics 2000 Jul-Aug;20(4):907-22; quiz 1106-7, 1112. doi: 10.1148/radiographics.20.4.g00jl07907. PMID: 10903683

Diagnosis

Congenital inner eyelid folds.
Millett M, Hyasat JG, Lueder GT
Ophthalmic Genet 2023 Aug;44(4):401-402. Epub 2023 Jan 13 doi: 10.1080/13816810.2022.2127151. PMID: 36636984
Congenital alacrima.
Zhao Z, Allen RC
Orbit 2022 Apr;41(2):162-169. Epub 2021 Sep 5 doi: 10.1080/01676830.2021.1974057. PMID: 34486478
Congenital dacryocystocele.
Pujari A
BMJ Case Rep 2016 Dec 9;2016 doi: 10.1136/bcr-2016-218029. PMID: 27941115Free PMC Article
The lacrimal system.
Örge FH, Boente CS
Pediatr Clin North Am 2014 Jun;61(3):529-39. doi: 10.1016/j.pcl.2014.03.002. PMID: 24852150
Branchio-oto-renal syndrome.
Jalil J, Basheer F, Shafique M
J Coll Physicians Surg Pak 2014 May;24(5):367-8. PMID: 24848399

Therapy

Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO).
Ali MJ
Prog Retin Eye Res 2023 Sep;96:101193. Epub 2023 Jul 1 doi: 10.1016/j.preteyeres.2023.101193. PMID: 37394093
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Surgical management of congenital nasolacrimal duct obstruction; one procedure for all versus all procedures for one.
Kashkouli MB, Karimi N, Khademi B
Curr Opin Ophthalmol 2019 Sep;30(5):364-371. doi: 10.1097/ICU.0000000000000584. PMID: 31219833
Thalidomide and misoprostol: Ophthalmologic manifestations and associations both expected and unexpected.
Miller MT, Ventura L, Strömland K
Birth Defects Res A Clin Mol Teratol 2009 Aug;85(8):667-76. doi: 10.1002/bdra.20609. PMID: 19639653
Congenital aberrant tearing: a re-look.
Miller MT, Strömland K, Ventura L
Trans Am Ophthalmol Soc 2008;106:100-15; discussion 115-6. PMID: 19277226Free PMC Article

Prognosis

Surgical management of congenital nasolacrimal duct obstruction; one procedure for all versus all procedures for one.
Kashkouli MB, Karimi N, Khademi B
Curr Opin Ophthalmol 2019 Sep;30(5):364-371. doi: 10.1097/ICU.0000000000000584. PMID: 31219833
Nasal and Lacrimal Sac Histopathology in Patients With Systemic Sarcoidosis Undergoing External Lacrimal Drainage Surgery.
Stewart CM, Luthert PJ, Rose GE
Ophthalmic Plast Reconstr Surg 2019 May/Jun;35(3):247-250. doi: 10.1097/IOP.0000000000001217. PMID: 30234834
Proboscis lateralis.
Lelli GJ Jr, Maher EA, Milite JP, Dyleski R
Ophthalmic Plast Reconstr Surg 2008 Nov-Dec;24(6):499-501. doi: 10.1097/IOP.0b013e31818b6e57. PMID: 19033859
Lymphoproliferative disorders of the ocular adnexa.
Cockerham GC, Jakobiec FA
Int Ophthalmol Clin 1997 Fall;37(4):39-59. doi: 10.1097/00004397-199703740-00005. PMID: 9429931
Paediatric dacryocystorhinostomy.
Hakin KN, Sullivan TJ, Sharma A, Welham RA
Aust N Z J Ophthalmol 1994 Nov;22(4):231-5. doi: 10.1111/j.1442-9071.1994.tb00789.x. PMID: 7727099

Clinical prediction guides

Lacrimo-auriculo-dento-digital syndrome with AIRE mutation: A case report.
Zhu H, Yu GY
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e988-e990. Epub 2022 Jul 21 doi: 10.1016/j.jormas.2022.07.014. PMID: 35870793
The Etiology of Epiphora: A Multifactorial Issue.
Nemet AY
Semin Ophthalmol 2016;31(3):275-9. Epub 2014 Nov 6 doi: 10.3109/08820538.2014.962163. PMID: 25375763
A lacrimal gland is a lacrimal gland, but rodent's and rabbit's are not human.
Schechter JE, Warren DW, Mircheff AK
Ocul Surf 2010 Jul;8(3):111-34. doi: 10.1016/s1542-0124(12)70222-7. PMID: 20712969
Congenital aberrant tearing: a re-look.
Miller MT, Strömland K, Ventura L
Trans Am Ophthalmol Soc 2008;106:100-15; discussion 115-6. PMID: 19277226Free PMC Article
Lacrimal outflow dysgenesis.
Yuen SJ, Oley C, Sullivan TJ
Ophthalmology 2004 Sep;111(9):1782-90. doi: 10.1016/j.ophtha.2004.02.011. PMID: 15350337

Recent systematic reviews

Assessing the success rate of treatment in simple and complex congenital nasolacrimal duct obstruction: a systematic review and meta-analysis.
Eshraghi B, Babaei L, Moradi M, Chaibakhsh S, Aghajani A
Graefes Arch Clin Exp Ophthalmol 2024 Jul;262(7):1993-2004. Epub 2023 Dec 7 doi: 10.1007/s00417-023-06318-4. PMID: 38059998
Phenotypic spectrum of FGF10-related disorders: a systematic review.
Bzdega K, Karolak JA
PeerJ 2022;10:e14003. Epub 2022 Sep 14 doi: 10.7717/peerj.14003. PMID: 36124135Free PMC Article
Nasolacrimal Duct Probing for Young Children With Congenital Nasolacrimal Duct Obstructions in China: A 10-Year Systematic Review.
Xiang Q, Gao X, Chen X, Qi J, Fang J
J Pediatr Ophthalmol Strabismus 2019 Nov 1;56(6):365-372. doi: 10.3928/01913913-20190923-04. PMID: 31743404

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