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Colorectal High Grade Intraepithelial Neoplasia

MedGen UID:
232092
•Concept ID:
C1333110
•
Neoplastic Process
Synonyms: Colorectal High-Grade Dysplasia; Colorectal High-Grade Intraepithelial Neoplasia; Large Intestinal High Grade Dysplasia; Large Intestinal High Grade Intraepithelial Neoplasia

Definition

A precancerous neoplastic process that affects the colon or rectum. It is characterized by moderate or severe epithelial dysplasia and complex architectural alterations of the mucosal epithelium. There is no evidence of invasion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal High Grade Intraepithelial Neoplasia

Professional guidelines

PubMed

Expected value of artificial intelligence in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
Messmann H, Bisschops R, Antonelli G, Libânio D, Sinonquel P, Abdelrahim M, Ahmad OF, Areia M, Bergman JJGHM, Bhandari P, Boskoski I, Dekker E, Domagk D, Ebigbo A, Eelbode T, Eliakim R, Häfner M, Haidry RJ, Jover R, Kaminski MF, Kuvaev R, Mori Y, Palazzo M, Repici A, Rondonotti E, Rutter MD, Saito Y, Sharma P, Spada C, Spadaccini M, Veitch A, Gralnek IM, Hassan C, Dinis-Ribeiro M
Endoscopy 2022 Dec;54(12):1211-1231. Epub 2022 Oct 21 doi: 10.1055/a-1950-5694. PMID: 36270318
Clinical results of infrared coagulation as a treatment of high-grade anal dysplasia: a systematic review.
Corral J, Parés D, García-Cuyás F, Revollo B, Videla S, Chamorro A, Piñol M, Clotet B, Sirera G
Tech Coloproctol 2019 Aug;23(8):707-712. Epub 2019 Jul 23 doi: 10.1007/s10151-019-02041-7. PMID: 31338711
Systematic review of guidelines for the assessment and management of high-grade anal intraepithelial neoplasia (AIN II/III).
Alam NN, White DA, Narang SK, Daniels IR, Smart NJ
Colorectal Dis 2016 Feb;18(2):135-46. doi: 10.1111/codi.13215. PMID: 26559167

Recent clinical studies

Etiology

A Novel Model Predicts Postoperative Pathology of Colorectal High-Grade Intraepithelial Neoplasia.
Yin Y, Wang T, Zhang P, Li C, Yang W, Lin Y, You J, Tao K
J Surg Res 2019 Aug;240:104-108. Epub 2019 Mar 25 doi: 10.1016/j.jss.2019.02.042. PMID: 30921664
Malignant recurrence and distal metastasis after complete local resection of colorectal "high-grade intraepithelial neoplasia": incidence and risk factors.
Wei XB, Xin L, Hao J
Int J Colorectal Dis 2014 Dec;29(12):1467-75. Epub 2014 Aug 26 doi: 10.1007/s00384-014-2001-0. PMID: 25155620

Diagnosis

A Novel Model Predicts Postoperative Pathology of Colorectal High-Grade Intraepithelial Neoplasia.
Yin Y, Wang T, Zhang P, Li C, Yang W, Lin Y, You J, Tao K
J Surg Res 2019 Aug;240:104-108. Epub 2019 Mar 25 doi: 10.1016/j.jss.2019.02.042. PMID: 30921664
Malignant recurrence and distal metastasis after complete local resection of colorectal "high-grade intraepithelial neoplasia": incidence and risk factors.
Wei XB, Xin L, Hao J
Int J Colorectal Dis 2014 Dec;29(12):1467-75. Epub 2014 Aug 26 doi: 10.1007/s00384-014-2001-0. PMID: 25155620

Prognosis

A Novel Model Predicts Postoperative Pathology of Colorectal High-Grade Intraepithelial Neoplasia.
Yin Y, Wang T, Zhang P, Li C, Yang W, Lin Y, You J, Tao K
J Surg Res 2019 Aug;240:104-108. Epub 2019 Mar 25 doi: 10.1016/j.jss.2019.02.042. PMID: 30921664
Malignant recurrence and distal metastasis after complete local resection of colorectal "high-grade intraepithelial neoplasia": incidence and risk factors.
Wei XB, Xin L, Hao J
Int J Colorectal Dis 2014 Dec;29(12):1467-75. Epub 2014 Aug 26 doi: 10.1007/s00384-014-2001-0. PMID: 25155620

Clinical prediction guides

A Novel Model Predicts Postoperative Pathology of Colorectal High-Grade Intraepithelial Neoplasia.
Yin Y, Wang T, Zhang P, Li C, Yang W, Lin Y, You J, Tao K
J Surg Res 2019 Aug;240:104-108. Epub 2019 Mar 25 doi: 10.1016/j.jss.2019.02.042. PMID: 30921664
Malignant recurrence and distal metastasis after complete local resection of colorectal "high-grade intraepithelial neoplasia": incidence and risk factors.
Wei XB, Xin L, Hao J
Int J Colorectal Dis 2014 Dec;29(12):1467-75. Epub 2014 Aug 26 doi: 10.1007/s00384-014-2001-0. PMID: 25155620

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