U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Streptococcal sore throat

MedGen UID:
508129
•Concept ID:
C0036689
•
Disease or Syndrome
Synonyms: Septic sore throat; Strep throat; strep throat; Strept throat; Streptococcal angina; Streptococcal Pharyngitis; Streptococcal pharyngitis; streptococcal pharyngitis; streptococcal sore throat
SNOMED CT: Strept throat (43878008); Strep throat (43878008); Streptococcal sore throat (43878008); Streptococcal pharyngitis (43878008); Septic sore throat (43878008); Streptococcal angina (43878008)
 
Monarch Initiative: MONDO:0021783

Definition

Inflammation of the throat due to Streptococcus pyogenes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStreptococcal sore throat

Professional guidelines

PubMed

Antibiotic treatment of children with sore throat.
Linder JA, Bates DW, Lee GM, Finkelstein JA
JAMA 2005 Nov 9;294(18):2315-22. doi: 10.1001/jama.294.18.2315. PMID: 16278359
Diagnosis and treatment of streptococcal sore throat.
Drug Ther Bull 1995 Feb;33(2):9-12. doi: 10.1136/dtb.1995.3329. PMID: 7587984
Evaluation of pharmacist management of streptococcal throat infections in a health maintenance organization.
Davis S
Am J Hosp Pharm 1978 May;35(5):561-6. PMID: 350043

Curated

UK NICE Diagnostics Guidance DG38, Rapid tests for group A streptococcal infections in people with a sore throat, 2019

Recent clinical studies

Etiology

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Prospective surveillance of streptococcal sore throat in a tropical country.
Steer AC, Jenney AW, Kado J, Good MF, Batzloff M, Magor G, Ritika R, Mulholland KE, Carapetis JR
Pediatr Infect Dis J 2009 Jun;28(6):477-82. doi: 10.1097/INF.0b013e318194b2af. PMID: 19483515
Cytolysin-dependent evasion of lysosomal killing.
Håkansson A, Bentley CC, Shakhnovic EA, Wessels MR
Proc Natl Acad Sci U S A 2005 Apr 5;102(14):5192-7. Epub 2005 Mar 28 doi: 10.1073/pnas.0408721102. PMID: 15795386Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385

Diagnosis

Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A
Int J Clin Pract 2017 Sep;71(9) Epub 2017 Sep 4 doi: 10.1111/ijcp.12961. PMID: 28869722
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Diagnosing streptococcal sore throat in adults: randomized controlled trial of in-office aids.
Worrall G, Hutchinson J, Sherman G, Griffiths J
Can Fam Physician 2007 Apr;53(4):666-71. PMID: 17872717Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Diagnosis and treatment of streptococcal sore throat.
Drug Ther Bull 1995 Feb;33(2):9-12. doi: 10.1136/dtb.1995.3329. PMID: 7587984

Therapy

Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Diagnosis and treatment of streptococcal sore throat.
Drug Ther Bull 1995 Feb;33(2):9-12. doi: 10.1136/dtb.1995.3329. PMID: 7587984
Streptococcal sore throat.
Hughes MH
Br Med J 1972 Aug 5;3(5822):349. doi: 10.1136/bmj.3.5822.349. PMID: 4558308Free PMC Article
Streptococcal sore throat.
Br Med J 1972 Jul 15;3(5819):132. PMID: 4557080Free PMC Article

Prognosis

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A
Int J Clin Pract 2017 Sep;71(9) Epub 2017 Sep 4 doi: 10.1111/ijcp.12961. PMID: 28869722
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Clinical prediction guides

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A
Int J Clin Pract 2017 Sep;71(9) Epub 2017 Sep 4 doi: 10.1111/ijcp.12961. PMID: 28869722
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Clinical course of suspected viral sore throat in young adults: cohort study.
Lindbaek M, Francis N, Cannings-John R, Butler CC, Hjortdahl P
Scand J Prim Health Care 2006 Jun;24(2):93-7. doi: 10.1080/02813430600638227. PMID: 16690557
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Recent systematic reviews

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2019
      UK NICE Diagnostics Guidance DG38, Rapid tests for group A streptococcal infections in people with a sore throat, 2019

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...