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Fetal macrosomia

MedGen UID:
8824
Concept ID:
C0015938
Finding
Synonyms: Fetal Macrosomia; Fetal Macrosomias; Macrosomia, Fetal; Macrosomias, Fetal
SNOMED CT: Fetal macrosomia (38206000); Fetal giant (38206000)

Definition

A fetus exceeding 4500 grams. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFetal macrosomia

Professional guidelines

PubMed

Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Salomon LJ, Alfirevic Z, Da Silva Costa F, Deter RL, Figueras F, Ghi T, Glanc P, Khalil A, Lee W, Napolitano R, Papageorghiou A, Sotiriadis A, Stirnemann J, Toi A, Yeo G
Ultrasound Obstet Gynecol 2019 Jun;53(6):715-723. doi: 10.1002/uog.20272. PMID: 31169958
Obstet Gynecol 2014 Mar;123(3):693-711. doi: 10.1097/01.AOG.0000444441.04111.1d. PMID: 24553167

Recent clinical studies

Etiology

Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Damhuis SE, Ganzevoort W, Gordijn SJ
Obstet Gynecol Clin North Am 2021 Jun;48(2):267-279. doi: 10.1016/j.ogc.2021.02.002. PMID: 33972065
Obstet Gynecol 2020 Jan;135(1):e18-e35. doi: 10.1097/AOG.0000000000003606. PMID: 31856124
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Kc K, Shakya S, Zhang H
Ann Nutr Metab 2015;66 Suppl 2:14-20. Epub 2015 Jun 2 doi: 10.1159/000371628. PMID: 26045324

Diagnosis

Nguyen MT, Ouzounian JG
Obstet Gynecol Clin North Am 2021 Jun;48(2):387-399. doi: 10.1016/j.ogc.2021.02.008. PMID: 33972073
Obstet Gynecol 2020 Jan;135(1):e18-e35. doi: 10.1097/AOG.0000000000003606. PMID: 31856124
Romero R, Kingdom J, Deter R, Lee W, Vintzileos A
Am J Obstet Gynecol 2018 Feb;218(2S):S608. doi: 10.1016/j.ajog.2018.01.010. PMID: 29422202Free PMC Article
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Neylon OM, Werther GA, Sabin MA
Curr Opin Pediatr 2012 Aug;24(4):505-11. doi: 10.1097/MOP.0b013e3283558995. PMID: 22705997

Therapy

Ye W, Luo C, Huang J, Li C, Liu Z, Liu F
BMJ 2022 May 25;377:e067946. doi: 10.1136/bmj-2021-067946. PMID: 35613728Free PMC Article
Pérez-Pérez A, Vilariño-García T, Guadix P, Dueñas JL, Sánchez-Margalet V
Nutrients 2020 Jul 2;12(7) doi: 10.3390/nu12071970. PMID: 32630697Free PMC Article
Yamamoto JM, Kellett JE, Balsells M, García-Patterson A, Hadar E, Solà I, Gich I, van der Beek EM, Castañeda-Gutiérrez E, Heinonen S, Hod M, Laitinen K, Olsen SF, Poston L, Rueda R, Rust P, van Lieshout L, Schelkle B, Murphy HR, Corcoy R
Diabetes Care 2018 Jul;41(7):1346-1361. doi: 10.2337/dc18-0102. PMID: 29934478
Kominiarek MA, Peaceman AM
Am J Obstet Gynecol 2017 Dec;217(6):642-651. Epub 2017 May 24 doi: 10.1016/j.ajog.2017.05.040. PMID: 28549978Free PMC Article
American College of Obstetricians and Gynecologists (College); Society for Maternal-Fetal Medicine, Caughey AB, Cahill AG, Guise JM, Rouse DJ
Am J Obstet Gynecol 2014 Mar;210(3):179-93. doi: 10.1016/j.ajog.2014.01.026. PMID: 24565430

Prognosis

Hillier TA, Pedula KL, Ogasawara KK, Vesco KK, Oshiro CES, Lubarsky SL, Van Marter J
N Engl J Med 2021 Mar 11;384(10):895-904. doi: 10.1056/NEJMoa2026028. PMID: 33704936Free PMC Article
Voormolen DN, DeVries JH, Sanson RME, Heringa MP, de Valk HW, Kok M, van Loon AJ, Hoogenberg K, Bekedam DJ, Brouwer TCB, Porath M, Erdtsieck RJ, NijBijvank B, Kip H, van der Heijden OWH, Elving LD, Hermsen BB, Potter van Loon BJ, Rijnders RJP, Jansen HJ, Langenveld J, Akerboom BMC, Kiewiet RM, Naaktgeboren CA, Mol BWJ, Franx A, Evers IM
Diabetes Obes Metab 2018 Aug;20(8):1894-1902. Epub 2018 May 8 doi: 10.1111/dom.13310. PMID: 29603547
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Boulvain M, Senat MV, Perrotin F, Winer N, Beucher G, Subtil D, Bretelle F, Azria E, Hejaiej D, Vendittelli F, Capelle M, Langer B, Matis R, Connan L, Gillard P, Kirkpatrick C, Ceysens G, Faron G, Irion O, Rozenberg P; Groupe de Recherche en Obstétrique et Gynécologie (GROG)
Lancet 2015 Jun 27;385(9987):2600-5. Epub 2015 Apr 8 doi: 10.1016/S0140-6736(14)61904-8. PMID: 25863654
Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS; Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group
N Engl J Med 2005 Jun 16;352(24):2477-86. Epub 2005 Jun 12 doi: 10.1056/NEJMoa042973. PMID: 15951574

Clinical prediction guides

Shulman Y, Shah BR, Berger H, Yoon EW, Helpaerin I, Mei-Dan E, Aviram A, Retnakaran R, Melamed N
Am J Obstet Gynecol MFM 2023 Aug;5(8):101042. Epub 2023 Jun 6 doi: 10.1016/j.ajogmf.2023.101042. PMID: 37286100
Jääskeläinen T, Klemetti MM
Nutrients 2022 Nov 13;14(22) doi: 10.3390/nu14224799. PMID: 36432486Free PMC Article
Wong SPW, Twynstra J, Gilliland JA, Cook JL, Seabrook JA
J Pediatr Adolesc Gynecol 2020 Apr;33(2):153-159. Epub 2019 Oct 18 doi: 10.1016/j.jpag.2019.10.006. PMID: 31634579
Araujo Júnior E, Peixoto AB, Zamarian AC, Elito Júnior J, Tonni G
Best Pract Res Clin Obstet Gynaecol 2017 Jan;38:83-96. Epub 2016 Sep 15 doi: 10.1016/j.bpobgyn.2016.08.003. PMID: 27727018
Pates JA, McIntire DD, Casey BM, Leveno KJ
J Ultrasound Med 2008 Jan;27(1):39-43. doi: 10.7863/jum.2008.27.1.39. PMID: 18096729

Recent systematic reviews

Ye W, Luo C, Huang J, Li C, Liu Z, Liu F
BMJ 2022 May 25;377:e067946. doi: 10.1136/bmj-2021-067946. PMID: 35613728Free PMC Article
Ribeiro MM, Andrade A, Nunes I
J Perinat Med 2022 Jan 27;50(1):4-17. Epub 2021 Sep 6 doi: 10.1515/jpm-2021-0315. PMID: 34478617
Vats H, Saxena R, Sachdeva MP, Walia GK, Gupta V
Obes Res Clin Pract 2021 Nov-Dec;15(6):536-545. Epub 2021 Nov 12 doi: 10.1016/j.orcp.2021.10.005. PMID: 34782256
Beta J, Khan N, Khalil A, Fiolna M, Ramadan G, Akolekar R
Ultrasound Obstet Gynecol 2019 Sep;54(3):308-318. Epub 2019 Aug 2 doi: 10.1002/uog.20279. PMID: 30938004
Goldstein RF, Abell SK, Ranasinha S, Misso M, Boyle JA, Black MH, Li N, Hu G, Corrado F, Rode L, Kim YJ, Haugen M, Song WO, Kim MH, Bogaerts A, Devlieger R, Chung JH, Teede HJ
JAMA 2017 Jun 6;317(21):2207-2225. doi: 10.1001/jama.2017.3635. PMID: 28586887Free PMC Article

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