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Renal cortical atrophy

MedGen UID:
871246
•Concept ID:
C4025730
•
Disease or Syndrome
HPO: HP:0002048

Definition

Atrophy of the cortex of the kidney. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal cortical atrophy

Conditions with this feature

Tubulointerstitial kidney disease, autosomal dominant, 2
MedGen UID:
358137
•Concept ID:
C1868139
•
Disease or Syndrome
Autosomal dominant tubulointerstitial kidney disease – MUC1 (ADTKD-MUC1) is characterized by slowly progressive tubulointerstitial disease that leads to end-stage renal disease (ESRD) and the need for dialysis or kidney transplantation. The rate of loss of kidney function for individuals is variable within and between families, with a median age of onset of end-stage renal disease (ESRD) of 46 years (range: ages 20-70 years). There are no other systemic manifestations.
See: Condition Record
Tubulointerstitial kidney disease, autosomal dominant, 2

Professional guidelines

PubMed

Antiphospholipid Syndrome Nephropathy: From Pathogenesis to Treatment.
Tektonidou MG
Front Immunol 2018;9:1181. Epub 2018 May 31 doi: 10.3389/fimmu.2018.01181. PMID: 29904380Free PMC Article
The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell-mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials.
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Drug-induced acute interstitial nephritis: pathology, pathogenesis, and treatment.
Krishnan N, Perazella MA
Iran J Kidney Dis 2015 Jan;9(1):3-13. PMID: 25599729

Recent clinical studies

Etiology

Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study.
Mizushima I, Yamamoto M, Inoue D, Nishi S, Taniguchi Y, Ubara Y, Matsui S, Yasuno T, Nakashima H, Takahashi H, Yamada K, Nomura H, Yamagishi M, Saito T, Kawano M
Arthritis Res Ther 2016 Nov 25;18(1):273. doi: 10.1186/s13075-016-1175-y. PMID: 27884179Free PMC Article
The significance of functional renal obstruction in predicting pathologic stage of upper tract urothelial carcinoma.
Amirian MJ, Radadia K, Narins H, Healy KA, Hubosky SG, Bagley D, Trabulsi EJ, Lallas CD
J Endourol 2014 Nov;28(11):1379-83. Epub 2014 Jul 16 doi: 10.1089/end.2014.0277. PMID: 24892728Free PMC Article
Erythropoietin-induced thrombosis as a result of increased inflammation and thrombin activatable fibrinolytic inhibitor.
Tobu M, Iqbal O, Fareed D, Chatha M, Hoppensteadt D, Bansal V, Fareed J
Clin Appl Thromb Hemost 2004 Jul;10(3):225-32. doi: 10.1177/107602960401000304. PMID: 15247979
Nephrolithiasis associated with renal insufficiency: factors predicting outcome.
Kukreja R, Desai M, Patel SH, Desai MR
J Endourol 2003 Dec;17(10):875-9. doi: 10.1089/089277903772036181. PMID: 14744353
Intrarenal reflux and renal damage.
Bourne HH, Condon VR, Hoyt TS, Nixon GW
J Urol 1976 Mar;115(3):304-6. doi: 10.1016/s0022-5347(17)59181-8. PMID: 1255892

Diagnosis

Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study.
Mizushima I, Yamamoto M, Inoue D, Nishi S, Taniguchi Y, Ubara Y, Matsui S, Yasuno T, Nakashima H, Takahashi H, Yamada K, Nomura H, Yamagishi M, Saito T, Kawano M
Arthritis Res Ther 2016 Nov 25;18(1):273. doi: 10.1186/s13075-016-1175-y. PMID: 27884179Free PMC Article
Erythropoietin-induced thrombosis as a result of increased inflammation and thrombin activatable fibrinolytic inhibitor.
Tobu M, Iqbal O, Fareed D, Chatha M, Hoppensteadt D, Bansal V, Fareed J
Clin Appl Thromb Hemost 2004 Jul;10(3):225-32. doi: 10.1177/107602960401000304. PMID: 15247979
Nephrolithiasis associated with renal insufficiency: factors predicting outcome.
Kukreja R, Desai M, Patel SH, Desai MR
J Endourol 2003 Dec;17(10):875-9. doi: 10.1089/089277903772036181. PMID: 14744353
Renal dysplasia in children with posterior urethral valves: a primary or secondary malformation?
Haecker FM, Wehrmann M, Hacker HW, Stuhldreier G, von Schweinitz D
Pediatr Surg Int 2002 Mar;18(2-3):119-22. doi: 10.1007/s003830100656. PMID: 11956776
Neonatal renal papillary and cortical necrosis.
Anand SK, Northway JD, Smith JA
Am J Dis Child 1977 Jul;131(7):773-7. doi: 10.1001/archpedi.1977.02120200055011. PMID: 879113

Therapy

Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study.
Mizushima I, Yamamoto M, Inoue D, Nishi S, Taniguchi Y, Ubara Y, Matsui S, Yasuno T, Nakashima H, Takahashi H, Yamada K, Nomura H, Yamagishi M, Saito T, Kawano M
Arthritis Res Ther 2016 Nov 25;18(1):273. doi: 10.1186/s13075-016-1175-y. PMID: 27884179Free PMC Article
Erythropoietin-induced thrombosis as a result of increased inflammation and thrombin activatable fibrinolytic inhibitor.
Tobu M, Iqbal O, Fareed D, Chatha M, Hoppensteadt D, Bansal V, Fareed J
Clin Appl Thromb Hemost 2004 Jul;10(3):225-32. doi: 10.1177/107602960401000304. PMID: 15247979

Prognosis

Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study.
Mizushima I, Yamamoto M, Inoue D, Nishi S, Taniguchi Y, Ubara Y, Matsui S, Yasuno T, Nakashima H, Takahashi H, Yamada K, Nomura H, Yamagishi M, Saito T, Kawano M
Arthritis Res Ther 2016 Nov 25;18(1):273. doi: 10.1186/s13075-016-1175-y. PMID: 27884179Free PMC Article
The significance of functional renal obstruction in predicting pathologic stage of upper tract urothelial carcinoma.
Amirian MJ, Radadia K, Narins H, Healy KA, Hubosky SG, Bagley D, Trabulsi EJ, Lallas CD
J Endourol 2014 Nov;28(11):1379-83. Epub 2014 Jul 16 doi: 10.1089/end.2014.0277. PMID: 24892728Free PMC Article
Nephrolithiasis associated with renal insufficiency: factors predicting outcome.
Kukreja R, Desai M, Patel SH, Desai MR
J Endourol 2003 Dec;17(10):875-9. doi: 10.1089/089277903772036181. PMID: 14744353
Renal dysplasia in children with posterior urethral valves: a primary or secondary malformation?
Haecker FM, Wehrmann M, Hacker HW, Stuhldreier G, von Schweinitz D
Pediatr Surg Int 2002 Mar;18(2-3):119-22. doi: 10.1007/s003830100656. PMID: 11956776

Clinical prediction guides

Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study.
Mizushima I, Yamamoto M, Inoue D, Nishi S, Taniguchi Y, Ubara Y, Matsui S, Yasuno T, Nakashima H, Takahashi H, Yamada K, Nomura H, Yamagishi M, Saito T, Kawano M
Arthritis Res Ther 2016 Nov 25;18(1):273. doi: 10.1186/s13075-016-1175-y. PMID: 27884179Free PMC Article
The significance of functional renal obstruction in predicting pathologic stage of upper tract urothelial carcinoma.
Amirian MJ, Radadia K, Narins H, Healy KA, Hubosky SG, Bagley D, Trabulsi EJ, Lallas CD
J Endourol 2014 Nov;28(11):1379-83. Epub 2014 Jul 16 doi: 10.1089/end.2014.0277. PMID: 24892728Free PMC Article
Nephrolithiasis associated with renal insufficiency: factors predicting outcome.
Kukreja R, Desai M, Patel SH, Desai MR
J Endourol 2003 Dec;17(10):875-9. doi: 10.1089/089277903772036181. PMID: 14744353
Renal dysplasia in children with posterior urethral valves: a primary or secondary malformation?
Haecker FM, Wehrmann M, Hacker HW, Stuhldreier G, von Schweinitz D
Pediatr Surg Int 2002 Mar;18(2-3):119-22. doi: 10.1007/s003830100656. PMID: 11956776

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